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After nearly 20 years of data, we can confidently say that there are no significant adverse cardiovascular complications

Lindstedt G, Lindstedt S (1970)

Obesity is a multi-systemic disease state with several associated complications such as musculoskeletal issues, obstructive sleep apnoea, cardiovascular disease, infertility, and cancer (endometrial, breast, ovarian, prostate, liver, gallbladder, kidney, and colon) as well as significant metabolic sequelae, the most important being type 2 diabetes due to its high morbidity and mortality through micro- and macro-vascular complications such as ischaemic heart disease, stroke, and peripheral vascular disease [3, 4]

"BPC-157 in musculoskeletal healing: Mechanisms and potential clinical applications." Front Pharmacol

P., Smith, A